Carprofen (Carodyl)

What is it?

Composition

Carodyl contains the active substance carprofen, which is a non-steroidal anti-inflammatory drug (NSAID). Carprofen is widely used in veterinary medicine due to its effectiveness in reducing pain and inflammation in dogs. The auxiliary components included in the drug help improve its digestibility and ease of administration, and also extend its shelf life.

The main action of carprofen is to inhibit the enzyme cyclooxygenase-2 (COX-2), which reduces the production of prostaglandins - substances that cause inflammation, pain and fever. It is important to note that carprofen acts selectively, minimally affecting cyclooxygenase-1 (COX-1), which reduces the likelihood of negative effects on the gastrointestinal tract and kidneys. Excipients in the composition ensure the stability of the drug, improve the taste and make it convenient to take.

• Carprofen is the main active ingredient, which has anti-inflammatory and analgesic effects.
• Stabilizers and fillers - ensure the preservation of the active substance and uniform distribution of the dosage.
• Flavoring agents - give the tablets an attractive taste, which makes them easier for animals to take.
• Binding components - help maintain the shape and integrity of the tablets.

How to use it?

Carodyl is used to treat inflammation and pain in dogs caused by various diseases of the musculoskeletal system. It is important to follow the recommended dosage and regimen to ensure maximum effectiveness and minimize the risk of side effects. The tablets have an attractive taste, which makes them easy to administer, but it is still recommended to give them with food to reduce the load on the stomach.

Before starting treatment, you must consult a veterinarian who will select the optimal dose depending on the weight and condition of the dog. Usually, the course of treatment lasts several days or weeks, but in some cases long-term therapy may be required. It is important not to exceed the prescribed dosage and not to interrupt the course without consulting a veterinarian.

1. The dosage is calculated based on the dogs weight. Usually 2-4 mg of carprofen per 1 kg of body weight is used, divided into 1 or 2 doses per day.
2. The tablets can be given with food or separately, depending on the dogs preferences. It is advisable to provide access to water.
3. The duration of treatment depends on the pets condition. Short-term use (several days) is recommended after surgery, and long-term use is recommended for chronic joint diseases.
4. If a dose is missed, do not double the dose. It is enough to give the next dose at the usual time.
5. Regular veterinary monitoring is required with long-term use to avoid possible complications.

How does it work?

Carodyl works due to the active substance carprofen, which is a non-steroidal anti-inflammatory drug (NSAID). Its main mechanism of action is to suppress the enzyme cyclooxygenase-2 (COX-2), which is responsible for the production of prostaglandins - substances that cause inflammation, pain and fever. Due to this, carprofen effectively reduces pain and inflammation, improving joint mobility and the general condition of the dog.

One of the main advantages of carprofen is its selective action. Unlike many other NSAIDs, it has a minimal effect on cyclooxygenase-1 (COX-1), which is involved in protecting the mucous membrane of the stomach and kidneys. This makes Carodyl safer compared to other drugs in this group, reducing the risk of gastrointestinal complications. However, despite this, with long-term use, it is important to monitor the dogs condition, especially if it has chronic diseases.

After oral administration, carprofen is quickly absorbed into the blood and begins to act within 1-2 hours. Its concentration in the body is maintained at a therapeutic level for 12-24 hours, which allows the drug to be used once or twice a day. It is metabolized in the liver and excreted mainly with bile and partly through the kidneys. Due to this, Carodyl is effective in the treatment of osteoarthritis, postoperative pain and traumatic injuries, allowing the dog to return to an active lifestyle faster.

Indications

Carodyl is used to relieve pain and inflammation in dogs caused by various diseases and conditions. It is especially useful for the treatment of chronic joint and bone diseases, as well as for the control of post-operative pain. The drug helps to improve mobility and quality of life in dogs suffering from osteoarthritis and other degenerative changes in the musculoskeletal system.

The main area of application is the treatment of inflammatory processes that occur in joint diseases, such as arthritis and hip dysplasia. In addition, Carodyl is often prescribed after surgery to reduce pain and speed up recovery. Veterinarians may also recommend the drug for injuries and bruises accompanied by inflammation and pain.

• Osteoarthritis and other chronic inflammatory joint diseases.
• Postoperative pain relief, especially after orthopedic and soft tissue surgeries.
• Trauma and inflammation in the musculoskeletal system.
• Conditions accompanied by acute or chronic pain.
• Maintaining an active lifestyle in older dogs with age-related changes in joints.

Contraindications

Despite the high efficiency of Carodyl, its use is limited by a number of contraindications that must be taken into account before starting treatment. The drug can cause adverse reactions in dogs with certain diseases or body characteristics, so it is important to consult a veterinarian first. Some conditions require special caution when taking carprofen, and in some cases its use is completely prohibited.

The main contraindications are associated with diseases of the gastrointestinal tract, since NSAIDs can have an irritating effect on the gastric mucosa. Carodyl is also not recommended for dogs with liver and kidney problems, since the drug is metabolized in these organs. In addition, it cannot be used in puppies under 6 weeks old and in animals with individual intolerance to carprofen.

• Peptic ulcers of the stomach and intestines, gastritis, tendency to bleeding.
• Severe liver and kidney disease, chronic renal failure.
• Allergic reaction to carprofen or other NSAIDs.
• Pregnancy and lactation in bitches.
• Concomitant use with other NSAIDs or corticosteroids.
• Serious cardiovascular disease.
• Puppies under 6 weeks of age or dogs with weakened immunity.

Side Effects

Like any medication, Carodyl may cause side effects, especially with prolonged use or when the recommended dosage is exceeded. Most dogs tolerate carprofen well, but some may experience adverse reactions from the digestive, cardiovascular, renal and nervous systems. It is important to closely monitor the pets condition and immediately contact your veterinarian if any alarming symptoms appear.

The most common side effects are related to the gastrointestinal tract. Non-steroidal anti-inflammatory drugs can irritate the gastric mucosa, leading to digestive disorders. In rare cases, allergic reactions, behavioral changes or kidney dysfunction are possible, especially in older dogs. Long-term use requires regular monitoring of blood tests to monitor the condition of the liver and kidneys.

• Digestive disorders: vomiting, diarrhea, loss of appetite, abdominal discomfort.
• Ulcerative lesions of the stomach and intestines, internal bleeding.
• Allergic reactions: itching, rashes, swelling.
• Changes in behavior: lethargy, irritability, weakness.
• Kidney dysfunction: increased thirst, frequent urination.
• Rarely - liver problems, expressed by yellowing of the mucous membranes.